Buy Semax: 5-10mg*10vials

Description

Semax Peptide (5mg / 10mg per vial) – 10 Vials per Box (High Purity Research Grade)

Elevate your neurochemical and cognitive research with our premium Semax box (10 vials per kit). Manufactured to exacting analytical standards, each box contains 10 individual sterile vials, available in customizable options of 5mg or 10mg of pure lyophilized Semax powder per vial (50mg to 100mg total active compound per box).

Whether your experimental protocols focus on neuroprotection, synaptic plasticity, brain-derived neurotrophic factor (BDNF) elevation, memory formation, or ischemic stress mitigation, our ultra-pure Semax peptide delivers the exceptional bio-potency, chemical stability, and reproducibility demanded by leading neuroscience laboratories.

Understanding Semax: The Next-Generation Nootropic Heptapeptide

Semax ($Met\text{-}Glu\text{-}His\text{-}Phe\text{-}Pro\text{-}Gly\text{-}Pro$ or $MEHFPGP$) is a synthetic analogue of the adrenocorticotropic hormone fragment $ACTH(4\text{-}7)$ attached to a C-terminal Prolyl-Glycyl-Proline ($PGP$) tripeptide tail. Developed by the Institute of Molecular Genetics at the Russian Academy of Sciences, Semax was strategically designed to harvest the powerful cognitive, neuroprotective, and regulatory effects of $ACTH$ without inducing any systemic steroidogenesis or adrenal hormone cascades.

The addition of the $PGP$ tripeptide sequence is a landmark innovation in peptide design. While native $ACTH$ fragments break down within seconds when exposed to blood and tissue peptidases, the stabilized $PGP$ extension shields Semax from rapid enzymatic cleavage. This structural modification drastically extends its biological activity, allowing it to penetrate brain structures and initiate long-lasting cellular signal transduction.

When you buy Semax 5mg or 10mg vials in a 10-vial box, you acquire a robust, stabilized neuropeptide widely studied across neurobiology, stroke recovery, and cognitive enhancement research.

Key Areas of Research & Biological Mechanisms

1. BDNF and NGF Neurotrophic Modulation

The primary signaling mechanism of Semax involves rapid, potent upregulation of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) along with their corresponding $TrkB$ receptor pathways.

• Neurogenesis & Plasticity: Promotes structural reorganization of dendrites, synaptic connections, and overall neuronal growth.

• Prefrontal & Hippocampal Focus: Specifically targets the hippocampus and prefrontal cortex, the core brain regions governing working memory, executive function, and spatial orientation.

2. Neuroprotective & Anti-Ischemic Properties

In models of cerebral ischemia, hypoxia, and traumatic brain injury, Semax exhibits significant protective properties.

• Infarct Volume Reduction: Limits neuronal necrosis and ischemic lesion spread during metabolic stress.

• Vascular Function Regulation: Modulates gene expression involved in smooth muscle, endothelial health, and cerebral microvascular perfusion.

• Suppression of Nitric Oxide Toxicity: Prevents excessive nitric oxide surge and reactive oxygen species (ROS) formation, preserving mitochondrial membrane integrity during oxidative shock.

3. Monoaminergic & Cholinergic neurotransmission

Semax modulates classical neurotransmitter systems to sharpen focus, mental energy, and learning efficiency without overstimulating the central nervous system like traditional stimulants.

• Dopamine & Serotonin Turnover: Enhances dopaminergic and serotonergic transmission in the striatum and cortex.

• Acetylcholine Release: Elevates hippocampal acetylcholine turnover, accelerating memory consolidation and cognitive processing speed.

4. Stress Resilience & Enkephalin Breakdown Inhibition

Semax helps regulate the Hypothalamic-Pituitary-Adrenal (HPA) axis under acute stress. By inhibiting enzymes that break down endogenous enkephalins, Semax supports natural stress adaptation, emotional stability, and mental stamina under high-workload research conditions.

Why Choose Our Semax 5mg / 10mg 10-Vial Box?

• Ultra-High Purity (>98%): Tested using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee precise sequence integrity and zero residual peptidase contamination.

• Flexible Dosing Options: Available in 5mg or 10mg per vial configurations (50mg–100mg total per 10-vial box) to accommodate custom research dosing protocols.

• Vacuum-Sealed Lyophilization: Freeze-dried in an inert environment to protect sensitive amino acid chains during storage and transit.

• Cost-Effective Bulk Kit: Purchasing a 10-vial package delivers a consistent, high-volume supply for longitudinal, multi-phase studies while minimizing overall laboratory expenses.

Technical Specifications

Specification	Details
Product Name	Semax ($Met\text{-}Glu\text{-}His\text{-}Phe\text{-}Pro\text{-}Gly\text{-}Pro$)
CAS Number	80714-61-0
Sequence	$MEHFPGP$ (ACTH 4-7 attached to Pro-Gly-Pro)
Molecular Formula	$C_{37}H_{51}N_{9}O_{10}S$
Molecular Weight	813.93 g/mol
Appearance	Fine white to off-white lyophilized cake/powder
Quantity Options	5mg or 10mg per vial / 10 vials per box (50mg–100mg total)
Purity Grade	>98% (HPLC Certified)
Storage Instructions	Store dry at -20°C for long term or 2°C – 8°C for short term.

Handling & Storage Guidelines

Keep un-reconstituted, lyophilized Semax vials stored at -20°C (or refrigerated at 2°C to 8°C in a dark setting). Avoid prolonged exposure to direct light, elevated room temperatures, or ambient humidity. Reconstitute under sterile laboratory conditions using sterile bacteriostatic water, deionized water, or specialized research intranasal buffer solutions depending on experimental goals. Once reconstituted, keep liquid solutions strictly refrigerated between 2°C and 8°C and use within the designated research window.