Buy LL37: 5-10mg*10 vials

Description

Introduction

LL-37 is a 37-amino acid cathelicidin-derived antimicrobial peptide studied extensively in laboratory research involving innate immunity, antimicrobial activity mechanisms, and immunomodulatory signaling pathways. As the only cathelicidin found in humans, LL-37 is used by researchers investigating the fundamental processes of host defense, wound healing biology, and immune cell communication in controlled experimental models.

What Is LL-37?

LL-37 is a naturally occurring 37-amino acid peptide with an amphipathic helical structure derived from the cathelicidin family of antimicrobial proteins. In research settings, it is examined for its broad-spectrum activity against bacteria, viruses, and fungi through membrane disruption mechanisms, as well as its immunomodulatory effects on host immune cells. Scientists study this compound to better understand how endogenous antimicrobial peptides coordinate innate immune responses and tissue repair processes in laboratory models.

Structure and Function

LL-37 is a 37-amino acid amphipathic helical peptide derived from the human cathelicidin hCAP18 protein. Its primary research function involves disrupting microbial membranes and modulating host immune cell activity including dendritic cell maturation and T-cell responses. Researchers also investigate its role in angiogenesis and wound healing pathway activation, making it relevant to studies in immunology, microbiology, and regenerative biology research.

Research Applications

LL-37 is of interest across several areas of scientific investigation, including:

• Antimicrobial mechanism studies examining efficacy against multidrug-resistant bacteria, viruses, and fungi
• Wound healing research exploring tissue regeneration acceleration and fibroblast activity modulation
• Immunomodulatory studies examining cytokine production, dendritic cell maturation, and T-cell response regulation
• Cancer research investigating tumor growth inhibition and apoptosis induction in cancer cell line models
• Biofilm disruption testing assessing penetration and eradication of microbial biofilms in chronic infection models

Research Findings and Scientific Interest

Studies have examined the role of LL-37 in antimicrobial membrane disruption and immune cell modulation, with findings pointing to its involvement in coordinating both innate and adaptive immune responses in laboratory models. Research into its wound healing and anti-biofilm properties continues to attract interest from the immunology, microbiology, and regenerative medicine research communities. Its broad-spectrum activity profile makes it a versatile tool for diverse in vitro and preclinical investigations.

Availability and Specifications

LL-37 is available in lyophilized powder form in 5mg and 10mg per vial configurations, supplied as 10 vials per set, for use in controlled laboratory environments by qualified researchers.

This product is intended strictly for laboratory research purposes only. It is not intended for human consumption or for medical, veterinary, or therapeutic use.